Dr Poole completed his undergraduate training at the University of Stellenbosch. Following internship and community service, he worked as a medical officer at Red Cross Children's Hospital, Cape Town. He commenced specialist paediatric training at the University of Stellenbosch where he spent one year at Worcester Hospital. Dr Poole commenced specialist paediatric pulmonology training at the University of Stellenbosch after having been awarded a Nycomed Training Fellowship in 2011. He has been in private practice at Milnerton Medi-clinic in Cape Town since 2013.
His interests include allergy-associated illness such as asthma, congenital and acquired lung disorders such as cystic fibrosis, and infectious diseases that affect the lung, such as tuberculosis. Dr Poole is also able to perform diagnostic and therapeutic bronchoscopies.